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Publications Based on the Familial Psoriasis Study

  1. Epidemiology and the genetics of psoriasis.
    Elder JT, Nair RP, Voorhees JJ.
    Journal of Investigative Dermatology 102:24S-27S, 1994.[abstract]
     
  2. Of genes and antigens: the inheritance of psoriasis.
    Elder JT, Henseler T, Christophers E, Voorhees JJ, Nair RP.
    Journal of Investigative Dermatology 103:150S-153S, 1994.[abstract]
     
  3. The genetics of psoriasis.
    Elder JT, Nair RP, Guo SW, Henseler T, Christophers E, Voorhees JJ.
    Archives of Dermatology 130:216-224, 1994.[abstract]
     
  4. Scanning chromosome 17 for psoriasis susceptibility: lack of evidence for a distal 17q locus.
    Nair RP, Guo SW, Jenisch S, Henseler T, Lange EM, Terhune M, Westphal E, Christophers E, Voorhees JJ, Elder JT.
    Human Heredity 45:219-230, 1995.[abstract]
     
  5. Evidence for Two Psoriasis Susceptibility Loci (HLA and 17q) and Two Novel Candidate Regions (16q and 20p) by Genome-wide Scan.
    Nair RP, Henseler T, Jenisch S, Stuart P, Bichakjian CK, Lenk W, Westphal E, Guo SW, Christophers E, Voorhees JJ, and Elder JT.
    Human Molecular Genetics 6:1349-1356, 1997.[abstract]
    Supplemental material
     
  6. Association of type I psoriasis with the Cw*0802-DRB1*0102-DQB1*0501 haplotype in North American multiplex families.
    Jenisch S, Nair RP, Henseler T, Elder JT, Marxen B, Krönke M, Westphal E.
    In: 12th International Histocompatibility Workshop and Conference Proceedings Genetic Diversity of HLA: Functional and Medical Implications. EDK, Serves, 1997.
     
  7. Linkage analysis of human leucocyte antigen (HLA) markers in familial psoriasis: strong disequilibrium effects provide evidence for a major determinant in the HLA-B/ -C region.
    Jenisch S, Henseler T, Nair RP, Guo SW, Westphal E, Stuart P, Kronke M, Voorhees JJ, Christophers E, Elder JT.
    American Journal of Human Genetics 63:191-199, 1998. [abstract]
    Supplemental material
     
  8. Linkage disequilibrium analysis of familial psoriasis: identification of multiple disease-associated MHC haplotypes.
    Jenisch S, Westphal E, Nair RP, Stuart P, Voorhees JJ, Christophers E, Kronke M, Elder JT, Henseler T.
    Tissue Antigens 53:135-146, 1999.     [abstract]
     
  9. Corneodesmosin gene polymorphism demonstrates strong linkage disequilibrium with HLA and association with psoriasis vulgaris.
    Jenisch S, Koch S, Henseler T, Nair RP, Elder JT, Watts CE, Westphal E, Voorhees JJ, Christophers E, Kronke M.
    Tissue Antigens54:439-449, 1999.     [abstract].
     
  10. Localization of psoriasis susceptibility Locus PSORS1 to a 60-kb Interval Telomeric to HLA-C
    Nair RP, Stuart P, Henseler T, Jenisch S, Chia NV, Westphal E, Schork NJ, Kim J, Lim HW, Christophers E, Voorhees JJ, Elder JT.
    American Journal of Human Genetics 66:1833-1844, 2000 .[abstract]
    Supplemental material
     
  11. S100A2 coding sequence polymorphism: characterization and lack of association with psoriasis
    Stoll SW, Chia NV, Nair RP, Woods TL, Stuart P, Henseler T, Jenisch S, Christophers E, Voorhees JJ, Elder JT.
    Clin Exp Dermatol. 26:79-83, 2001. [abstract]
     
  12. Variations in the HCR (Pg8) gene are unlikely to be causal for familial psoriasis.
    Chia NV, Stuart P, Nair RP, Henseler T, Jenisch S, Lim HW, Christophers E, Voorhees JJ, Elder JT.
    Journal of Investigative Dermatology 116:823-824, 2001. [full text]
     
  13. The genetics of psoriasis 2001: the odyssey continues.
    Elder JT, Nair RP, Henseler T, Jenisch S, Stuart P, Chia N, Christophers E, Voorhees JJ.
    Arch Dermatol. 137:1447-1454, 2001. [full text] 
     
  14. Lack of association between NOD2 3020InsC frameshift mutation and psoriasis
    Nair RP, Stuart P, Ogura Y, Inohara N, Chia NV, Young L, Henseler T, Jenisch S, Christophers E, Voorhees JJ, Nunez G, Elder JT.
    Journal of Investigative Dermatology 117:1671-672, 2001. [full text]
     
  15. Analysis of phenotypic variation in psoriasis as a function of age at onset and family history
    Stuart P, Malick F, Nair RP, Henseler T, Lim HW, Jenisch S, Voorhees JJ, Christophers E, Elder JT.
    Archives of Dermatilogical Research 294:207-213, 2002. [abstract] [full text]
     
  16. The international psoriasis genetics study: assessing linkage to 14 candidate susceptibility loci in a 942 affected-sib-pair cohort
    International Psoriasis Genetics Consortium (Allen M, Barker JNWN, Bowcock AM, Burden AD, Chia N, Capon F, Christophers E, Daly MJ, Elder JT, Helms C, Henseler T, Jenisch S, Menter A, Mistry R, Nair RP, Stuart PE, Tillman D, Trembath RC, Veal C, Voorhees JJ)
    American Journal of Human Genetics 73:430-437, 2003. [abstract] [full text]
     
  17. Meta-Analysis of Genome-Wide Studies of Psoriasis Susceptibility Reveals Linkage to Chromosomes 6p21 and 4q28-q31 in Caucasian and Chinese Hans Population
    Sagoo GS, Tazi-Ahnini R, Barker JW, Elder JT, Nair RP, Samuelsson L, Traupe H, Trembath RC, Robinson DA, Iles MM
    Journal of Investigative Dermatology 122:1401-405, 2004. [abstract] [full text]
     
  18. The MHC genes in psoriasis
    Elder JT, Nair RP, Weichenthal M, Stuart P, Voorhees JJ, Christophers E, Jenisch S
    Current Genomics 6:39-43, 2005. [full text]
     
  19. Fine mapping of the psoriasis susceptibility gene PSORS1: A reassessment of risk associated with a putative risk haplotype lacking HLA-Cw6
    The Cluster 17 Collaboration (Abecasis GR, Allen M, Barker JNWN, Burden D, Capon F, Christophers E, Elder JT, Fischer J, Giardina E, Gudjonsson JE, Hüffmeier U, Jenisch S, Karason A, Kere J, Nair RP, Novelli G, Prud'homme J-F, Qin ZS, Samuelsson L, Sanchez F, Saarialho-Kere U, Ståhle M, Stuart P, Tilman D, Traupe H, Trembath R, Valdimarsson H, Veal C, Voorhees JJ, Weichenthal M)
    Journal of Investigative Dermatology 124:921-930, 2005. [abstract] [full text]
     
  20. Protein tyrosine phosphatase gene PTPN22 polymorphisms in psoriasis: lack of evidence for association
    Nistor I, Nair RP, Stuart PE, Hiremagalore R, Thompson RA, Jenisch S, Weichenthal M, Abecasis GR, Qin S, Christophers E, Lim HW, Voorhees JJ, and Elder JT
    Journal of Investigative Dermatology 125:395-396, 2005. [full text]
     
  21. Analysis of RUNX1 binding site and Raptor polymorphisms in psoriasis: no evidence for association despite adequate power and evidence for linkage
    Stuart PE, Nair RP, Abecasis GR, Nistor I, Hiremagalore R, Chia NV, Qin ZS, Thompson RA, Jenisch S, Weichenthal M, Janiga J, Lim HW, Christophers E, Voorhees JJ, and Elder JT
    Journal of Medical Genetics 43:12-17, 2005. [abstract] [full text] [request reprint]
     
  22. Sequence and Haplotype Analysis Supports HLA-C as the Psoriasis Susceptibility 1 Gene
    Nair RP, Stuart PE, Nistor I, Hiremagalore R, Chia NVC, Jenisch S, Weichenthal M, Abecasis GR, Lim HW, Christophers E, Voorhees JJ, and Elder JT
    American Journal of Human Genetics 66:827-851, 2006. [abstract] [full text] [request reprint]
    Supplemental material

  23. Polymorphisms of the IL12B and IL23R genes are associated with psoriasis
    Nair RP, Ruether A, Stuart PE, Jenisch S, Tejasvi T, Hiremagalore R, Schreiber S, Kabelitz D, Lim HW, Voorhees JJ, Christophers E, Elder JT, and Weichenthal M
    Journal of Investigative Dermatology 128:1653-1661, 2008. [abstract] [full text] [request reprint]
  24. Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathway
    Nair RP, Duffin KC, Helms C, Ding J, Stuart PE, Goldgar D, Gudjonsson JE, Li Y, Tejasvi T, Feng BJ, Ruether A, Schreiber S, Weichenthal M, Gladman D, Rahman P, Schrodi SJ, Prahalad S, Guthery SL, Fischer J, Liao W, Kwok PY, Menter A, Lathrop GM, Wise CA, Begovich AB, Voorhees JJ, Elder JT, Krueger GG, Bowcock AM, Abecasis GR; Collaborative Association Study of Psoriasis
    Nature Genetics 41:199-204, 2009. [abstract] [request reprint]

  25. Genome-wide association scan yields new insights into the immunopathogenesis of psoriasis
    Elder JT
    Genes and Immunity 10:201-209, 2009. [abstract] [request reprint]

  26. Psoriasis bench to bedside: genetics meets immunology
    Nair RP, Ding J, Duffin KC, Helms C, Voorhees JJ, Krueger GG, Bowcock AM, Abecasis GR, Elder JT
    Archives of Dermatology 145:462-464. [no abstract available] [request reprint]

  27. Global Gene Expression Analysis Reveals Evidence for Decreased Lipid Biosynthesis and Increased Innate Immunity in Uninvolved Psoriatic Skin
    Gudjonsson JE, Ding J, Li X, Nair RP, Tejasvi T, Qin ZS, Ghosh D, Aphale A, Gumucio DL, Voorhees JJ, Abecasis GR, Elder JT
    Journal of Investigative Dermatology 2009 July. [Epub ahead of print]. [abstract] [request reprint]